๐Ÿ’จ 1.3 Mucosal Defense System

Cards (13)

  • What does GALT stand for?
    Gut-associated lymphoid tissue
  • What are Peyer's patches?
    Organized aggregates of lymphoid tissue
  • What are the two primary functions of GALT?
    Protect against pathogens and permit tolerance
  • What types of pathogens does GALT protect against?
    Bacteria, protozoans, and viruses
  • Why is immunologic tolerance important in the GI tract?
    To tolerate dietary substances and resident bacteria
  • What is significant about the GI tract's area?
    Largest area in contact with pathogens
  • Where are 80% of immunoglobulin-producing cells found?
    In the small intestine
  • What is the role of nonimmunologic defense?
    Protect against luminal pathogens
  • What are some components of nonimmunologic defense?
    Gastric acid, mucin, peristalsis, permeability
  • What is the effect of impaired small intestinal peristalsis?
    Higher levels of bacteria in the intestine
  • What can result from higher levels of bacteria in the small intestine?
    Diarrhea or steatorrhea
  • What is steatorrhea?
    Increased fecal fat excretion
  • What is the clinical manifestation of impaired intestinal peristalsis called?
    Blind loop syndrome or stagnant bowel syndrome