ANATOMICAL AND SPECIAL LAB

• Anatomical Pathology Laboratory is the section in the laboratory which is focused on the disease diagnosis based on the gross, microscopic, immunohistochemical, and molecular examination of body tissues and solid tissue specimens.
• Special staining, also known as histochemistry, is the use of special stains to determine the chemical compounds and their distribution within and in between the biological cells of the body.
• Breast Panel consists of biomarkers that are important in the genetic testing for breast cancer, including estrogen receptor assay, progesterone receptor assay, C-erb-2 (Her2- neu) p-53, and DNA ploidy analysis.
• Autopsy is a method of obtaining specimens from the dead (morgue).
• Anatomical Pathology Laboratory is the section in the laboratory which is focused on the disease diagnosis based on the gross, microscopic, immunohistochemical, and molecular examination of body tissues and solid tissue specimens.
• Autopsy is a method of obtaining specimens from the dead (morgue).
• Biopsy is a method of obtaining specimens from an alive person (O.R.).
• Biopsy is a method of obtaining specimens from an alive person (O.R.).
• Numbering is the process of recording the tissue specimen in a log book and assigning identification numbers to the specimen received in the laboratory.
• Numbering is the process of recording the tissue specimen in a log book and assigning identification numbers to the specimen received in the laboratory.
• Fixation is the preservation of the tissue specimen in as lifelike manner as possible, routine fixative is 10% formalin.
• Special staining, also known as histochemistry, is the use of special stains to determine the chemical compounds and their distribution within and in between the biological cells of the body.
• Breast Panel consists of biomarkers that are important in the genetic testing for breast cancer, including estrogen receptor assay, progesterone receptor assay, C-erb-2 (Her2- neu) p-53, and DNA ploidy analysis.
• Dehydration is the process of removing water from the specimen by using increasing grades of alcohol.
• Fixation is the preservation of the tissue specimen in as lifelike manner as possible, routine fixative is 10% formalin.
• Clearing, also known as de-alcoholism, is the removal of excess alcohol in the tissues and making the tissues transparent, routine clearing agent is xylene.
• Dehydration is the process of removing water from the specimen by using increasing grades of alcohol.
• Infiltration is the process of filling up tissue spaces or cavities using melted paraffin wax.
• Embedding/Molding is the process of placing the infiltrated tissue inside a mold, melted paraffin wax is poured over the tissue and allows it to solidify.
• Clearing, also known as de-alcoholism, is the removal of excess alcohol in the tissues and making the tissues transparent, routine clearing agent is xylene.
• Trimming is the removal of excess paraffin wax from the block until it assumes the shape of a truncated pyramid.
• Infiltration is the filling up of tissue spaces or cavities using melted paraffin wax.
• Sectioning, also known as Microtomy, is the process of cutting the tissue into thin slices called ribbons/sections using a microtome, after sectioning, ribbons are placed on a floatation water bath and fished out using tissue adhesive and glass slide.
• Embedding/Molding is the process of placing the infiltrated tissue inside a mold, melted paraffin wax is poured over the tissue and allows it to solidify.
• Staining is the use of hematoxylin and eosin dyes to differentiate the cells and cellular constituents.
• Polymerase Chain Reaction is a technique used to amplify specific, target DNA fragments from low quantities of source DNA or RNA (after a reverse transcription step to produce complimentary copies of DNA).
• Genome Sequencing is a laboratory procedure that determines the order of bases in the genome of an organism in one process to decipher the genetic material found in an organism.
• Pathologist is a person who reads and collects data from anatomic, medtech only process the specimens.
• Cryostat is a modification of a microtome used in the laboratory.
• Paraffin wax is a hydrophobic (insoluble) substance used in the laboratory.
• Immunohistochemical staining involves detecting antigens in the cells by using the principle of antibodies binding to specific antigens.
• Alcian blue, Congo red, oil red O, periodic acid-schiff are chemicals used in tissues to stain certain components.
• Tissue block is the process of putting mold (paraffin wax) into the tissue.
• Sectioning is the use of a microtome in the laboratory.
• Post mortem examination, also known as autopsy or necropsy, is used to determine the cause of death, to evaluate any disease or injury that may have been present.
• Molecular Diagnostics, also known as Molecular Biology and Biotechnology Diagnostics or Molecular Laboratory, primarily uses different enzymes and other reagents, DNA and RNA are identified and sequenced to detect any pathologic conditions/disease process.
• Gel Electrophoresis is a procedure that separates molecules on the basis of their rate of movement through a gel under the influence of an electrical field.
• Special Laboratory Immunohistochemistry is a special section of the laboratory that combines anatomical, clinical, and biochemical techniques where antibodies (monoclonal and polyclonal) bounded to enzymes and fluorescent dyes are used to detect the presence of antigens in tissue.
• Frozen section is a section of tissue that is processed after sectioning and is used within 3-4 hours.
• Tissue processor is an automated machine used in the laboratory.