The human body has two communication systems: the nervous system and the endocrine system.
The endocrine system sends hormones (chemical messengers) around the body.
When hormones reach a target tissue, they produce a response.
The endocrine system is made up of glands which secrete hormones directly into the bloodstream.
Urea is produced from the breakdown of excess amino acids in the liver.
Tissue typing allows us to check if an organ is compatible with the recipient before transplantation, which can lead to long waits for an organ but can prevent organ rejection.
The pituitary gland secretes hormones into the blood to either influence the body or act on other glands to stimulate them to produce different hormones.
The pancreas secretes insulin which controls blood glucose levels.
The thyroid gland secretes thyroxine which controls metabolic rate, heart rate and temperature.
The adrenal gland secretes adrenaline which is involved in the 'fight or flight' response.
The ovary secretes oestrogen which is involved in the menstrual cycle and the development of female secondary sexual characteristics.
The testes secretes testosterone which is involved in the production of sperm and the development of male secondary sexual characteristics.
The blood transports the hormone to a target organ or tissue where it has an effect.
Compared to the nervous system, the hormonal system is much slower but it acts for longer.
Adrenaline is a hormone that is produced by the adrenal glands to prepare the body for a flight or flight response.
A flight-or-flight response is the body’s response to a dangerous situation: historically this would have been being confronted by a dangerous animal, for example.
Aspects of the fight or flight response include increased heart rate, increased blood pressure, increased flow to muscles, and increased blood sugar levels.
Thyroxine regulates metabolic rate, which is important in growth and development.
The levels of thyroxine are controlled by negative feedback.
The menstrual cycle prepares for a potential pregnancy and begins with the lining of the uterus breaking down, leading to a woman having her period.
The layer then builds up again, until ovulation occurs, at which point an egg is released from the ovary and moves to the uterus via the fallopian tube.
If a fertilised egg has not been embedded in the lining after 28 days and the cycle continues, it is controlled by four hormones: Follicle stimulating hormone (FSH), oestrogen, luteinising hormone (LH), and progesterone.
Hormonal methods of contraception include the contraceptive pill, the contraceptive patch, and the contraceptive implant.
Vasoconstriction means blood does not flow so close to the surface, resulting in less heat lost.
If the glucose levels are too high, the pancreas produces the hormone insulin.
Type 2 diabetes: the body cells no longer respond to insulin, this condition is acquired and blood glucose levels can rise to a fatal amount.
Sweating stops, skeletal muscles contract rapidly (shivering) to generate heat from respiration, hairs stand on end to create an insulating layer, trapping warm air.
The urinary system is the bodily system that removes impurities and waste products from our blood.
The main organ of the urinary system is the kidney.
Blood containing impurities travels in the renal artery to the kidneys.
Vasodilation means more blood flows closer to the surface of the skin, resulting in increased energy transfer from the body.
Any excess is sent to the ureter for excretion, and eventually the bladder.
Glucose to move from the blood into muscle cells for respiration, and excess glucose to be converted into glycogen which is stored in the liver.
Type 1 diabetes: the pancreas cannot produce enough insulin, this condition is congenital and blood glucose level can rise to a fatal amount.
The kidneys regulate the levels of salt, ions and urea in the blood.
Diabetes is a disease where the body cannot control blood sugar levels properly.
Obesity is a risk factor for Type 2 diabetes.
The kidney is supplied by the renal artery and a renal vein takes blood away.
The purified blood returns to the circulation by way of the renal vein.
The ureter carries from kidneys to the bladder to be excreted out the body.