Evidence Based Medicine

• What is evidence based medicine (EBM)?

  Clinical discipline that claims to bring the best evidence from clinical and health care research to the bedside, the surgery or clinic, and the community
• What is evidence based practice (EBP)?


  approach to health care where health professionals use the best evidence possible (most appropriate info available) to make clinical decisions for individual patients.
• What is Reproducibility?

  the result of a study should be achieved again with a high degree of agreement when the study is replicated with the same methodology by different researchers
• What is Sensitivity?


  probability that a test result will be positive when the disease is present (true positive rate)
• What is Specificity?

  the probability that a test result will be negative when the disease is not present (true negative rate)
• Positive predictive value: The likelihood that a patient with a positive test has a disease.
• Negative predictive value: The likelihood that a patient with a negative test does not have a disease
• Studies in field of EVIDENCE-BASED PRACTICE?

  • therpeutic interventions
  • diagnostic tests
  • etiology
  • prognosis
  • clinical practice guidelines
• How can we EVALUATE the DIAGNOSTIC METHODS?

  • technical capacity of methods
  • diagnostic accuracy
  • diagnostic impact
  • therapeutic impact
  • patient outcome
  • optimal usage
• RULE of REPEATING EXAMINATIONS

  Never inspect the uncertain value of the test in an other laboratory. Your uncertainty will only increase duse to different "Bayes" between labs.
• Fill in the blanks

  A) TP/TP+FN

  B) TN/TN+TP

  
• Fill the blanks.

  A) TP/TP+FP

  B) TN/TN+FN

  
• RULE savings on the cost of QUALITY

  A cheaper and less quality test will always cause more money and time loss than the savings from its use
• RULE OF INCORRECT INDICATION

  If a doctor complains that his results do not match the clinical diagnosis, it may be his fault
• Methods of evaluation of the optimal usage

  • SWOT
  • Cost-benefit analysis
  • Cost-utility analysis
  • Social return of investments analysis
  • Risk-benefit analysis
• Fill the blanks

  A) strengths

  B) weaknesses

  C) opportunities

  D) threats