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Cells
Cell Recognition and the Immune System
Phagocytosis
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What is a phagocyte?
A
macrophage
that carries out
phagocytosis
.
Where are phagocytes found?
In the
blood
and tissues.
What triggers phagocytosis?
Any
non-self
cell that is detected.
How do phagocytes find pathogens?
They are
attracted
by any
chemicals
or
debris
released by the
pathogens.
What do the receptors on the surface of phagocytes allow?
For phagocytes to attach to
antigens
on the surface of
pathogens.
Once attached to a pathogen, the phagocyte...
Changes shape to move around it and engulfs the
pathogen
.
Once the pathogen is engulfed, what is it contained in?
A vesicle called a
phagosome
.
What within the phagocyte fuses with the phagosome?
A
lysosome
containing
digestive enzymes
.
What does the lysosome release into the phagosome?
The enzyme
lysozyme
which
hydrolyses
the pathogen. The pathogen is destroyed.
What happens to the soluble products of phagocytosis?
They are
absorbed
and used by the phagocyte.