It’s the only usable form of chemical energy in the human body
What does ATP consist of?
Adenosine, 3 phosphate and a ribose sugar
How long does ATP last for?
2 - 3 seconds
What is the Sarcolemma?
The cellmembrane of the muscle cell
What is the sarcoplasm?
The cytoplasm of a muscle cell. Contains ATP, glycogen and Phosphocreatine.
What is Glycolysis?
The breakdown of glucose into pyruvate producing energy for re-synthesis of ATP
What are the three energy systems?
ATP-PC system
Anaerobicglycolytic system
aerobic system
What are the two parts of the ATP-PC system?
PC -> P + C + energy
ADP + P + energy -> ATP
What and why are the ATP-PC reactions referred to as?
A coupled reaction because
Step 1 is Exothermic
Step 2 is Endothermic
What happens to PC after it is used?
Creatinine migrates from cells into blood, into the kidneys and then excreted as urine
What are some disadvantages of using the ATP-PC system?
One molecule of PC means only one molecule of ATP re-synthesized
Stores only last for 5 - 8 seconds of high-intensity exercise
PC can only be re-synthesized in presence of oxygen
What is the facilitating enzyme for ATP?
ATPase
Where is the high energy bond in ATP?
Between the second and thirdphosphate groups.
What do the energy systems used primarily and only do?
Re-synthesizeATP
What enzyme breaks down Phosphocreatine?
Creatinekinase
Where does the ATP-PC system re-synthesize ATP?
In the Sarcoplasm
Where does the Anaerobic glycolytic system resynthesize ATP?
In the sarcoplasm
What enzyme is activated when PC stores are low and what does it do?
GlycogenPhosphorylase
It breaks down muscle glycogen converting it to glucose
How is glucose broken down?
Through glycolysis and using the enzyme phosphofructokinase
This breaks it down into :
2Pyruvicacid molecules
4Hydrogen ions
What happens after the break down of glucose due to there being no available Oxygen?
Hydrogen ions build up creating an acidic environment which denatures enzymes causing muscle pain
What is pyruvic acid converted to during the end stages of anaerobic glycolytic system?
It is converted to lactic acid via the enzyme Lactatedehydrogenase
How long can the anaerobic glycolytic system be sustained?
10 seconds - 3 minutes
What are some of the advantages of the ATP-PC system?
No oxygen required
Energy is released rapidly
Excellent for short / high intensity events (e.g 100m sprint)
PC can be resynthesized quickly (50% in 30 secs and 100% in less than4 mins)
System can be extended through creatine supplements
How much energy does glycolysis release?
Enough energy to resynthesize 2 ATP molecules
What are the advantages of the anaerobic glycolytic system?
ATP can be resynthesized quickly
Lasts longer than the ATP-PC system
The lactic acid produced can be converted back into glycogen or used as fuel via oxidation into carbondioxide and water
Its useful for sprint finishes
What are the disadvantages of the anaerobic glycolytic system?
The by-product of Lactic acid which accumulates creating an acidic environment which denatures enzymes preventing them from increasing rate of reaction
Only a small amount of energy is released from glycogen under anaerobic conditions