Listeria causes diseases in several animal species including humans, with symptoms including febrile gastroenteritis, bacteremia, brain stem and cranial nerve dysfunction, and placentitis.
Listeria is a Gram-positive intracellular pathogen that can be treated with Ampicillin (200 mg/kg per day, IV), Chlortetracycline (10 mg/kg per day for 5 days, IV), Penicillin (44,000 U/kg per day for 7 days, IM), Trimethoprim-sulphmethoxazole (10 mg/kg per day, IV).
Surface structures of Erysipelothrix include a capsule (lipopolysaccharide, slime or glycocalyx) for resistance to phagocytosis, and surface protective proteins (spA, B and C antigens) for biofilm formation, adhesion, and to elicit immune response.
Erysipelothrix is the problem of pigs, ruminants, and turkey, it is zoonotic/humans, and it causes a characteristic purplish, swollen, painful, hardened rash known as erysipeloid.
Enzymes of Erysipelothrix include neuraminidase (sialidase) for bacterial attachment, invasion, destroy blood vessels leading to hemorrhage and thrombosis, and hyaluronidase for spreading via destroying hyaluronic acid and polysaccharides between adjacent cells.
Erysipelothrix rhusiopathiae is characterized by alpha-hemolytic colonies on blood agar, heart infusion agar with sodium azide & crystal violet for plating pig sample and incubated for 48h, ferments glucose, lactose producing acid but not maltose and mannitol, and produces H2S.
Humans can be infected with Erysipelothrix due to occupational zoonotic disease, people who have contact with pigs, poultry, fish (vets, abattoir workers, butchers, farmers), and it causes a purple-colored hardened finger swelling.