The bimolecular phospholipid layer acts as a barrier to water soluble molecules such as glucose or amino acids , lipids soluble molecules can dissolve in the membrane
Proteins in the membrane form channels or act as carriers to transport such molecules , these channels are selective due to specific shape and size
Diffusion that occurs aided by protein channels and carriers is called facilitated diffusion
Active transport using ATP from respiration allows movement against a concentration gradient , enzymes catalyse the reactions of active transport
Cholesterol in the membrane affects its permeability and fluidity , it stabilises the membrane
Unsaturated fatty acids ( less hydrogen ) increase permeability