Erasmus Darwin established the Lunar Society, a group of inventors, scientists and manufacturers, which played a central role in developing the Industrial Revolution in the West Midlands.
In his poems and prose work Zoonomia1794-6, Erasmus Darwin wrote about the nature of organic life and set out the theory of development that anticipates his Grandson's later evolutionary ideas in 1859.
Percy Shelley places Erasmus Darwin as an authority figure who thinks that the events of the story are ‘not an impossible occurrence’ in the preface of Frankenstein.
Percy Shelley is referring to the idea of live matter occurring from dead matter, alike Darwin’s report of how the mixture of flour and water appeared to come to life by spontaneous generation, which Mary refers to in the introduction of the 1831 version of the novel.
Victor Frankenstein's intervention in natural processes, which from a Christian view usurps the power of creation reserved for god, also in Darwin’s terms interrupts these processes.
Victor Frankenstein's use of chemicals to put together the creature ignores the natural cycle for the creation of new life, and so his creature an evolutionary step backwards.
He sets out a theory of its development that anticipates the evolutionary ideas that his grandson Charles sets out in On the Origin of Species (1859)
Darwin believed that life might emerge through:
Spontaneous generation
Species reproducing by a solitary paternal process
Reproduction by hermaphroditic creatures
However, he believed that in evolutionary terms these were not ideal, and that sexual reproduction, requiring the combination of both a male and female parent, was the most advanced evolutionary level of reproduction.