Anne K Mellor argues that Sheley believes there is both a good and bad side of science and these can be associated with feminine and masculine attitudes.
Scientific language, especially of the 17th century assume that nature is feminine, science is masculine, and they exist in a sexual relation that may not be consensual.
Erasmus Darwin’s proto-evolutionary conception of nature states that both female and male seeds are required to ensure the necessary characteristics of the species were passed on.
Victor completely disrupts this natural process as he removed the female contribution to the creature’s creations and denies the creature maternal love and nurture because of this.
The monster destroys everyone close to Frankenstein and these deaths of innocent and loving individuals is the condemnation of Victor's regressive and destructive life as a scientist.