Diagnostic reagent strips as biosensers

• immobilised enzymes that work by producing a colour change of a chemical reaction into s electrical signal. These immobilised enzymes act as diagnostic tools.
• for example, Clinistix.

  This works by using GLUCOSE OXIDASE and another enzyme PER-OXIDASE.

  Peroxidase catalyses the breakdown of Hydrogen Peroxide which is produced by glucose oxidase). The oxygen reacts with the colour dye producing a colour change in the strip.
• Intensity of the colour in Clinistix indicates concentration of glucose
• Another example is glucose meters. This measures the level of glucose in a blood droplet on the strip.

  
  

  The amount of gluconic acid made by glucose oxidase is turned into a electrical signal.

  
  

  It is then converted into a digital readout