Diathesis-Stress Model — A diathesis is a biological vulnerability. However not everyone with these ‘candidate’ genes will develop a disorder. The expression of the gene depends on experience in the form of a stressor which triggers the condition (a diathesis). This has been illustrated by Tienari et al who studied 145 Finnish adoptees whose mothers had schizophrenia and were then matched with a sample of 158 adoptees without this genetic risk.