SAP Pathology

• SAP:

  • a clinical manifestation of coronary artery obstruction when the obstruction is large enough to impair blood supply to such an extent that the myocardium doesn’t receive the oxygen it requires to meet its own metabolic needs
  • As a consequence, the myocardium becomes ischaemic
  • Ischaemia is most likely to occur where myocardial metabolic demands exceed the capacity of the obstructed artery to supply an adequate blood supply
• SAP:

  • Myocardial ischaemia is associated with 2 consequences; firstly, producing the chest pain of angina, secondly increasing the risk of electrical instability and therefore the likelihood of producing cardiac arrhythmias including sustained ventricular tachycardia / ventricular fibrillation