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A-level Biology
Structure of triglycerides and phospholipids
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Max Mottram
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What are triglycerides?
Fats
found in our bodies and food
What are the components that make up triglycerides?
Glycerol
connected to three
fatty acids
How do triglycerides differ from other types of lipids?
They consist of
glycerol
and three
fatty acids
What type of bonds does a saturated fatty acid have?
Only single
carbon-carbon
bonds
What is the typical saturation state of the fatty acids in a phospholipid?
One is
saturated
, the other is
unsaturated
How is a fatty acid classified as saturated or unsaturated?
Based on their
carbon bonding
What do the fatty acids in phospholipids make the other end?
Hydrophobic
(water-fearing)
What part of the phospholipid repels water?
The green tails made of
fatty acids
Why are phospholipids described as amphipathic?
They have both
hydrophilic
and
hydrophobic
regions
What is the role of the glycerol backbone in a triglyceride?
It serves as the foundation for
fatty acid
attachment
What is the name of the part of the molecule that is repelled by water?
Hydrophobic
tail
What type of bonds does an unsaturated fatty acid contain?
At least one
double bond
between
carbons
How many carbons are in the glycerol backbone of a triglyceride?
Three
carbons
How does the attachment of fatty acids to glycerol occur in triglycerides?
Each fatty acid joins at one of glycerol's
OH
groups
How are fatty acids attached to the glycerol backbone?
Via
ester bonds
at the
OH groups
What role does the cell membrane structure play?
Provides framework for
proteins
and molecules
How does fluidity benefit the cell membrane?
It allows lateral movement of
components
What are the two types of fatty acids?
Saturated
and
unsaturated
What type of bonds connect fatty acids to glycerol in triglycerides?
Ester bonds
What are the key differences between triglycerides and phospholipids?
Triglycerides have three
fatty acids
; phospholipids have two.
Triglycerides lack a
phosphate group
; phospholipids have one.
Triglycerides are
hydrophobic
; phospholipids are
amphipathic
.
Triglycerides primarily store energy; phospholipids form
cell membranes
.
What is the general structure of a phospholipid?
A phospholipid has a similar structure to
triglyceride
, but with only 2
fatty acids
and a
phosphate
in addition
What does barrier control in cell membranes regulate?
Substance
movement
What is the structural base for both phospholipids and triglycerides?
Glycerol
What is the nature of phospholipids?
Amphipathic
What part of the phospholipid is attracted to water?
The red head containing a
phosphate group
How many fatty acids are present in triglycerides?
Three
fatty acids
What is the difference between Interstitial Fluid and Cytosolic Fluid?
Interstitial Fluid (
Extracellular
) is the fluid found between cells
Cytosolic Fluid (
Intracellular
) is the fluid found inside cells
How do phospholipids compare to triglycerides in terms of structure?
Phospholipids have 2 fatty acids; triglycerides have 3.
Phospholipids contain a
phosphate group
; triglycerides do not.
Both have a
glycerol structure
base.
What is a glycolipid?
Lipid with
carbohydrate
attached
What does hydrophobic mean?
Water-fearing
What is the purpose of the cytoskeletal filaments in the cell membrane?
To provide
structural support
What is the role of cholesterol in the cell membrane?
To regulate
fluidity
and
permeability
What is a glycoprotein?
Protein with
carbohydrate
attached
If you wanted to study the detailed 3D structure of the cell membrane, which microscope technique would you use?
Scanning electron microscope
(SEM)
How do the functions of integral membrane proteins and peripheral membrane proteins differ?
Integral membrane proteins:
Embedded within the
phospholipid bilayer
Involved in transport, signaling, and cell-cell interactions
Peripheral membrane proteins:
Associated with the surface of the membrane
Involved in anchoring the membrane to the cytoskeleton
Why is the dual nature of phospholipids essential?
It is crucial for
membrane formation
What orientation do the hydrophobic tails of phospholipids have in the bilayer?
They
point
inward
What orientation do the hydrophilic heads of phospholipids have in the bilayer?
They face outward toward
water
Do triglycerides contain a phosphate group?
No
,
they
do
not
What are the key functions of cell membranes?
Barrier control
: Selectively
permeable
Fluidity
: Allows lateral movement
Structure: Framework for
proteins
Protection: Boundary between
interior
and exterior
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