DNA hybridisation can be used to compare the DNA of different organisms, extracting, purifying, cutting DNA from two species, labelling one with a radioactive or fluorescent marker, mixing, heating to separate the strands, cooling to allow the strands to combine, separating out hybrid strands, increasing temperature to measure the degree that the two strands are linked, and if the species are closely related they will share complementary bases and more H bonds linking them in the hybrid strand.