Antibody
Cards (58)
- Two forms of antibodies?
- Who formulated the side chain theory?
- This antibody diversity theory says that, antigen is produced and it will select a proper receptor for it. And upon interaction it will break off and become antibodies, and the cell will produce new receptor to replace it.
- Who formulated the instructive theory?
- Who formulated the clonal selection theory?
- This theory proposes that individual lymphocytes are genetically pre programmed to generate a specific antibody?
- What is the major drawback of of the clonal theory?
- Who proposed that the genes coding for the constant and the variable regions of IG regions are separate?
- Received the Nobel prize when he discovered the genetic mechanism of antibody diversity?
- What chromosome codes for the heavy chains of antibodies?
- What chromosome codes for the gene of kappa (k) light chains?
- What chromosome codes for the lambda (λ) light chains?
- What region of the antibody makes determines the specificity of it?
- What is a classic monomeric antibody structure composed of?
- What kind of chemical bond, bonds the light chain to the heavy chains?
- What kind of chemical bond, binds the heavy chains together?
- This is a unique amino acid sequence that is common to all IG molecules of a given class in each specie?
- What are the 5 possible isotypes of an antibody?
- This is a minor variation in the heavy chain sequences that are present in some individuals but not the others?
- This is the variable portion of each chain and that is unique to a specific antibody molecule, this gives the specificity of an antibody?
- What do you call the recognition domain of an antibody chain and that binds to the epitope of an antigen?
- How many paratopes can be present in a single monomer?
- Papain treatment of an antibody can yield how many fragments? Namely?
- In pepsin treatment of an antibody, how many fragments are produced? namely?
- F(ab')2 is a result of pepsin treatment, how many Fab units does it have and how many antigens can it bind?
- This antibody is also known as the macroglobulin?
- How many monomers does IgM have?
- Where is IgM confined to?
- This immunoglobulin is the primary immune response antibody and is the first to elevate if there is an infection?
- This is other wise known as the immune antibody?
- How many subclasses does IgG have?
- What IgG subclass is has the least concentration in the serum?
- What is the ONLY IgG subclass that cannot cross the placenta?
- What is the first IgG subclass to do complement binding?
- What IgG subclasses responses to protein antigenic stimulation?
- What IgG subclasses responses to polysaccharide antigenic stimulation?
- What IgG subclass has the greatest number of Disulfide bonds at the hinges? How many S-S bonds does it have?
- What Ig can participate in agglutination reactions?
- Between IgG and IgM, what does best in agglutination reactions?
- Between IgG and IgM, what does best in precipitation reaction?