Simoun is Crisóstomo Ibarra reincarnated as a wealthy jeweler, bent on starting a revolution.
Basilio is Sisa's son, now an aspiring doctor.
Isagani is Basilio's best friend; portrayed as emotional and reactive; Paulita Gómez' boyfriend before being dumped for fellow student Juanito Peláez.
KabesangTales is Telesforo Juan de Dios, a former cabeza de barangay (barangay head) who resurfaced as the feared Luzón bandit Matanglawin (Tagalog for Hawkeye); his father, Old Man Selo.
Don Custodio or Custodio de Salazar y Sánchez de Monteredondo is a famous journalist who was asked by the students about his decision for the Academia de Castellano.
Paulita Gómez is the girlfriend of Isagani and the niece of Doña Victorina, the old India who passes herself off as a Peninsular, who is the wife of the quack doctor Tiburcio de Espadaña.
Father Florentino is Isagani's godfather, and a secular priest; was engaged to be married, but chose the priesthood instead.
Huli or Juliana de Dios is the girlfriend of Basilio and the youngest daughter of Kabesang Tales.
BenZayb or Abraham Ibañez is his real name; a journalist who thinks he is the only one thinking in the Philippines.
Placido Penitente is a student of the University of Santo Tomas who is always miserable, and therefore controls his temper.
Quiroga is a Chinese businessman who dreamt of being a consul of a Consulate of China in the Philippines; hid Simoun's weapons inside his house.
Old Man Selo is the father of Kabesang Tales; raised the sick and young Basilio after his mother Sisa had died.
Father Fernandez is the priest-friend of Isagani; promised to Isagani that he and the other priests will give in to the students' demands.
Attorney Pasta is one of the great lawyers of mid-Hispanic Manila.
Captain-General is the powerful highest official of the Philippines.
Padre Sibyla or Hernando de la Sibyla, a Filipino friar and now vice-rector of the University of Santo Tomas (U.S.T.).