krebs cycle

• Krebs Cycle, also known as Citric Acid Cycle or Tricarboxylic Acid Cycle (TCA), is a cyclical series of oxidation reactions that give off CO2 and produce one ATP per cycle.
• Krebs Cycle requires Oxygen (Aerobic).
• Krebs Cycle turns twice per glucose molecule.
• Krebs Cycle produces 2 ATP.
• Krebs Cycle is used to generate energy through oxidation of ACETYL COA, synthesis of NADH, and production of amino acids.
• Krebs Cycle takes place in the mitochondria of the eukaryotes and the cytosol of the prokaryotes.
• The product of Krebs Cycle is 3 NADH, 2 CO2, 1 FADH2, 1 GTP.
• All NADH and CO2 produced in Krebs Cycle will proceed to the electron transport chain to make ATP.
• If acetyl is included in the Krebs Cycle, the number of NADH will be 4.
• The formation of Acetyl CoA involves the oxidation of pyruvate to acetyl CoA, the translocation of pyruvate molecules from the cytosol into the mitochondrion by a carrier protein in the mitochondrial membrane, the removal of a CO2 from pyruvate, the attachment of coenzyme A, and the combination of acetyl CoA and oxaloacetate (4 carbon compound).
• The process of Krebs involves synthesis/condensation, isomerization, oxidative decarboxylation, gtp synthesis, redox reaction, hydration, and redox reaction.
• In the first step of Krebs, acetyl coenzyme A and oxaloacetate (4 carbon compound) are combined, resulting in the removal of acetyl coa.
• In the second step of Krebs, a hydroxyl group is transferred.
• In the third step of Krebs, oxidative decarboxylation occurs, resulting in the loss of carbon in the form of carbon dioxide.
• In the fourth step of Krebs, fumarate is formed (4 carbon).
• In the fifth step of Krebs, succinate is formed (4 carbon).
• In the sixth step of Krebs, GTP synthesis occurs, resulting in the removal of coenzyme A because it makes the cycle unstable.
• In the seventh step of Krebs, succinate is oxidized, resulting in the formation of fumarate (4 carbon).
• In the eighth step of Krebs, fumarate is hydrated, resulting in the formation of malate (4 carbon).
• In the ninth step of Krebs, malate is oxidized, resulting in the formation of aspartate (4 carbon).
• In the tenth step of Krebs, aspartate is oxidized, resulting in the formation of fumarate (4 carbon).