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Topic 5: Health, Disease and the Development of Medicines
5.3 Vaccination and Antibiotics
5.3.2 Antibiotics
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Antibiotics stop
bacterial
growth or kill them.
True
What type of action does tetracycline exhibit against bacteria?
Bacteriostatic
What is a disadvantage of broad-spectrum antibiotics?
They kill beneficial gut bacteria
Which type of antibiotic is less likely to cause resistance?
Narrow-spectrum
Antibiotic resistance occurs when bacteria evolve the ability to survive antibiotic exposure.
True
What are bacteria resistant to multiple antibiotics called?
Superbugs
Antibiotics work by either killing bacteria directly or inhibiting their
growth
Bacteriostatic antibiotics prevent bacterial growth by interfering with protein
production
Categorize the two main types of antibiotics by their range of effectiveness:
1️⃣ Broad-spectrum antibiotics
2️⃣ Narrow-spectrum antibiotics
Narrow-spectrum antibiotics reduce the risk of resistance because they minimize impact on gut
bacteria
Which antibiotic is an example of a bacteriostatic agent?
Erythromycin
What is the primary cause of antibiotic resistance?
Overuse of antibiotics
What are superbugs resistant to?
Multiple antibiotics
Phage therapy uses viruses to target specific
bacteria
What is the primary goal of antibiotic stewardship?
Preserve antibiotic effectiveness
What are antibiotics used to treat?
Bacterial infections
What type of medications are antibiotics different from?
Antiseptics and antivirals
Antibiotics target
bacterial
cells without harming human cells.
True
Narrow-spectrum antibiotics minimize harm to gut bacteria but require accurate
diagnosis
Bactericidal antibiotics like penicillin destroy bacteria by disrupting their
cell walls
What is a primary cause of antibiotic resistance?
Overuse of antibiotics
Match the factor with its explanation in the development of antibiotic resistance:
Overuse of antibiotics ↔️ Excessive use allows resistant strains to thrive
Misuse of antibiotics ↔️ Not completing the prescribed course
Natural bacterial evolution ↔️ Bacteria evolve to resist antibiotics
Antibiotics are the same as antiseptics and antiviral drugs.
False
What does selective toxicity in antibiotics refer to?
Targeting bacteria without harming human cells
Match the type of antibiotic with its characteristic:
Broad-spectrum ↔️ Effective against a wide range of bacteria
Narrow-spectrum ↔️ Targets specific types of bacteria
What are the two primary mechanisms by which antibiotics work against bacteria?
Bactericidal and bacteriostatic
Misuse of antibiotics, such as stopping early when feeling better, can lead to
resistance
.
True
Superbugs pose a significant threat to public health due to their resistance to multiple
antibiotics
.
True
What is one key preventative measure to reduce antibiotic resistance?
Improve hygiene and sanitation
Antibiotic stewardship principles include prescribing antibiotics only when
necessary
Antibiotics work by either killing bacteria directly or inhibiting their
growth
Antibiotics like penicillin kill bacteria by disrupting their
cell wall
Match the type of antibiotic with its description:
Broad-spectrum ↔️ Acts against a wide variety of bacteria
Narrow-spectrum ↔️ Targets specific types of bacteria
Order the steps of how antibiotics work against bacteria:
1️⃣ Antibiotic targets bacterial cell wall or protein synthesis
2️⃣ Bactericidal antibiotics kill bacteria directly
3️⃣ Bacteriostatic antibiotics inhibit growth
4️⃣ Selective toxicity prevents harm to human cells
What do bacteriostatic antibiotics like tetracycline prevent in bacteria?
Protein synthesis
Not completing the prescribed course of antibiotics allows surviving bacteria to develop
resistance
What are antibiotics used to treat?
Bacterial infections
Match the antibiotic mechanism with its action:
Bactericidal ↔️ Kill bacteria directly
Bacteriostatic ↔️ Inhibit bacterial growth
Antibiotics demonstrate
selective toxicity
to protect human cells.
True
What is a major disadvantage of broad-spectrum antibiotics?
They can kill beneficial gut bacteria
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