W1: Signal Transduction in Prokaryotes - Quorum Sensing

Subdecks (2)

Cards (25)

  • quorum sensing refers to the ability of bacteria to detect the presence of other bacteria using chemical cues and respond accordingly
  • cooperative interactions between bacteria allow them to coordinate beneficial group activities like biofilms
  • antagonistic interactions between bacteria allow them to exclude species that are detrimental to the community like antibiotic production
  • bacterial communities can be homo or hetero geneous
  • bacteria communicate with each other using chemical signals (quorum) such as AHL, AIP, or AI2
  • bacteria will form communities in high signal density areas
  • autoinducer 2 (AI2) are produced for interspecies communication between bacteria
  • AI2 is the most common quorum sensing molecule for interspecies communication made by LuxS signal synthase, chemical structure differs between aquatic (phosphosensor/phosphorelay, has boron) and terrestrial (similar to AHL, diffusion) bacteria
  • quorum sensing here is extrinsic (diffuses out then in), digital (all/nothing), autocrine/paracrine