Diffusion is the net movement of particles from an area of higher concentration to an area of lower concentration
The concentration gradient is the path from an area of higher concentration to an area of lower concentration. Particles diffuse down a gradient
Diffusion is a passive process - when molecules diffuse directly through a cell membrane its also known as simple diffusion
The rate of diffusion depends on
The concentration gradient - the higher it is the faster the rate of diffusion. As diffusion takes a place the difference between the two sides decrease until it reaches an equilibrium
The thickness of the exchange surface - the thinner the exchange surface the shorter the distance for diffusion - faster rate of diffusion
The surface area - the larger the surface area, the faster the rate of diffusion
Facilitated diffusion moves down a concentration gradient, from a higher to lower concentration. It is also a passive process - it doesn't use energy. There are two types of proteins involved: channel proteins, carrier proteins
Carrier proteins moves large molecules across the membrane down their concentration gradient. Different carrier proteins facilitate the diffusion of different molecules
First a large molecule attaches to a carrier proteins binding site in the membrane
Then the protein changes shape
This releases the molecule on the opposite side of the membrane
Channel proteins form pores in the membrane for charged particles to diffuse through.
Different channel proteins facilitate the diffusion of different charged particles
Factors affecting the rate of facilitated diffusion
The concentration gradient - the higher the concentration gradient the faster the rate of facilitated diffusion. As equilibrium is reached the rate of facilitated diffusion will level off
The number of channel or carrier proteins - once all the proteins in a membrane are in use, facilitated diffusion can't happen any faster even if you increase the concentration gradient