MOLGENLAB A1: HIstory

• Gregor Mendel

  • Father of Modern Genetics
  • Mendelian Genetics
  • Pisum sativum
• Wilhelm Johannsen

  • coined "gene"
  • and other genetic terminologies
• Thomas Hunt Morgan

  • Fruit fly experiment
  • Sex-linked inheritance
• George Beadle and Edward Tatum

  • "one gene, one enzyme"
  • Neurospora mold
  • radiation
• Barbara McClintock

  Discovered transposons, which are small sections of DNA that can move around the genome, maize
• Alfred Hershey and Martha Chase

  • Blender Experiment
  • radioactive chemicals
  • protein vs dna as genetic material
• James Watson, Francis Crick, Maurice Wilkins:

  Gathered data to construct a 3d model of DNA Structure
• Rosalind Franklin:

  x ray crystallography
• Marshall Nirenberg and Heinrich Matai:

  synthesized protein in lab and deciphered 64 triplets of protein code
• Werner Arber and Hamilton Smith:

  Restriction enzymes using bacteriophages
• Alec Jeffreys:

  minisatellite DNA used for DNA fingerprinting
• Craig Venter:

  team leader for Human Genome Project