Translocation

• What is NON-RECIPROCAL translocation?

  occurs when a segment of chromosome breaks and rejoins either to the other end of the same chromosome or another non-homologous chromosome
• What is RECIPROCAL translocation?

  occurs when two non-homologous chromosomes break and exchange fragments
• does not involve loss of genetic information, rearrangement of existing genes
• expression of gene altered due to relocation, change in phenotype