Red blood cell Anomalies

• semilunar body


  Frequently seen in malaria and in other conditions causing overt hemolysis.
• Semilunar body

  As large as leukocytesPale-pink staining ghost of the red cell (the membrane remaining after the contents been released)
• Bronze Ellipoc yte


  Bipolar or central distribution of hemoglobin
• Biscuit cells


  Hemoglobin sc disease
• Biscuit cell

  Folded RBCS
• Thalassemia


  also known as Mediterranean Anemia
• Thalassemia


  also known as Hereditary leptocytosis
• Target cells

  ThalassemiaLCAT deficiency
• Bite cell


  demonstrate a semicircular defect in their edge (resembles a bite mark)
• Bite cell


  aka degmacyte
• bell shaped


  in vivo, and on electron microscopy, these cell appears_ --- shape
• codocyte


  are RBCS with an increased cell membrane to volume ratio
• target cells

  RBCS which show a centrally stained area with a thin outer rim of hemoglobin
• target cells

  platy cyte, Bull's eye cell, Mexican hat cell, Greek helmet cell
• target cells

  aka codocyte
• Oat-shaped cells


  Which form of depranocyte has less pronounced projections, and returns to its original shape once reoxygenated.
• ISC

  crescent shaped with long projectionswhen re oxygenated they fragment
• irreversible sickle cell and oat shaped cell

  two forms of depranocyte
• Drepanocyte


  sickle or crescent shaped RBCS
• Drepanocyte


  sickle cell or Menisocyte
• Schistocytes

  uremiaMAHASHUS
• TTP, HELLP, HUS, and DIC

  major MAHAS
• MAHAS

  Group of disorders characterized by RBC fragmentation and thrombocytopenia
• Schistocytes

  Fragmented RBCs
• Schistocytes


  aka schizocyte
• Dacryocyte

  PMFmegaloblastic anemiathalassemia
• Dacryocyte


  Pear-shaped or teardrop shaped RBCs
• Dacryocyte


  aka teardrop cells
• Hereditary ElliptocytosisThalassemia

  Elliptocyte
• Elliptocytes

  elliptical (cigarshaped) RBC
• Ovalocytes


  oval shaped RBCs
• Ovalocyte


  aka southeast asian ovalocyte
• TAR syndrome

  Thrombocytopenia absent radius
• Burr cell


  uremia and pk deficiency
• Burr cell


  RBCS with regularly speculated surface
• Burr cells


  aka echinocytes
• Abetalipoproteinemia

  Bassen kornzweig syndrome or Hereditary Acanthocytosis
• Acanthocyte


  AbetalipoproteinemiaMcleod syndrome Pk deficiency
• Acanthocyte


  RBC with irregularly spiculated surface
• Acanthocytes


  aka thorn cell