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Pharma (lec)
Pain management
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Created by
Briaa
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Cards (29)
Pain
:
External
; May come on
quickly
and it's more
difficult
to
ignore
Ache
:
Internal
;
Persistent
physical discomfort, typically
dull
Hurt
: Accidentally cause
pain
or
injury
(can be
emotional
or
physical
)
Pain
is a
unpleasant sensory
and
emotional experience
associated with
actual
or
potential tissue injury
Primarily a
protective
mechanism (
acute
pain)
Transduction
is the cause of the
pain
and
site
of the pain
Noxious
(
harmful
) stimuli cause
release
of
chemicals
due to the
tissue injury
Amount of
pain
is related to the amount of
tissue
injury
Transmission
:
Movement
of
pain
impulses from the site of
transduction
to the
brain
A:
Large
,
myelinated
,
fast rate conduction
, produces
fast
pain,
acute
pain
C:
Unmyelinated
,
smallest
diameter fiber,
slowest
rate of conduction, produces
slow
pain,
chronic
pain,
slow
in onset but and
longer
in duration
Fast
pain:
Sharp
,
localized
, large
myelinated
,
cerebral cortex
Slow
pain:
Dull
,
generalized
, small
unmyelinated
,
visceral
pain
Cutaneous
:
Sharp burning pain
, origin in
skin
or
subcutaneous
tissue
Deep
: More
diffuse
and
throbbing
, origin in
body
structures
Perception
: Is recognized, defined, and responded to
nociceptive
input is seen as
pain
in the brain
Smaller
receptive field =
Greater
discriminative ability
Large
receptor field =
Decreased
discriminative ability
Pain threshold
:
Lowest intensity
at which a stimulus is perceived as
pain
Perceptual dominance
:
Intense pain
at one location may
increase
the
threshold
in another location
Modulation
: How the body
ability
to respond and
alter
to the pain
Referred
pain: Site of pain is
different
from its point of
origin
but
innervated
by the same
spinal segment
Nonopioid analgesics
: Isn't addictive (
Acetaminophen
,
Nonselective
NSAIDs,
COX-2
selective NSAIDs
Opioid analgesics
: Can cause an
addiction
(
Morphine
,
fentanyl
,
hydromorphone
, and
oxycodone
)
Adjuvant
analgesics
: More
advance
(
Local
anesthetics,
anticonvulsants
,
antidepressants
)
Treatment
: Targeting any of the three phases (
Transmission
,
perception
,
modulating
)
Mild
pain:
1-3
on a scale of
0-10
Mild
to
moderate
pain:
4-6
on a scale of
0-10
Moderate
to
severe
pain:
4-10
on a scale of
0-10