The small intestine, comprised of the duodenum, jejunum, and ileum, is a 22-foot muscular tube that breaks down food using enzymes and bile. Peristalsis moves and mixes the contents. The duodenum initiates breakdown, while the jejunum and ileum absorb nutrients. The contents change from semi-solid to liquid with water, bile, enzymes, and mucus. After nutrient absorption, the liquid moves to the large intestine (colon).