Poxvirus, Filovirus.

• Poxvirus, genus Filovirus, have the uncoating mechanism.
• Poxvirus are not known to have diffusion tendencies.
• Poxvirus are interested in the satellite lymph nodes.
• Orthopoxvirus includes human smallpox.
• Monkeypox is a papule/cutaneous disease characterized by papule eruptions.
• Parapoxvirus is associated with pseudosmallpox of bovis, causing nodule cutaneous lesions.
• Yabapoxvirus is associated with tanapox, causing nodule cutaneous lesions.
• Molluscipoxvirus is associated with molluscum contagiosum, exclusive of man, causing papule or macule-papule lesions in the epidermis of the hand and superior limbs.
• Molluscipoxvirus is not known to transmit through swimming pools.
• Molluscipoxvirus causes benign tumors, which are hypertrophy of the epidermis, never in the dermis.
• Marburg virus is associated with hemorrhagic fever, causing early symptoms of dyspnea, edema, conjunctival injection, exanthema, CNS symptoms like encephalitis, delirium, apathy, and later symptoms of bloody stool, ecchymoses, visceral hemorrhage and hematemesis.
• Ebola virus is also associated with hemorrhagic fever, causing early symptoms of fever, sore throat, muscle pain, headaches, and later symptoms of vomit, diarrhea, rash, liver and kidney malfunctions.
• Ebola virus may also develop macule- papule rash.
• Diagnosis of Poxvirus and Filovirus infections is clinical.
• Treatment for Poxvirus and Filovirus infections is surgical asportation.
• Ribovirus, genus Filovirus, have the RNA monocatenated with – polarity, RNA polymerases with RNA dependency, and interact with the cytoplasmic membrane, entering through endocytosis and then freed in plasma.
• Diagnosis of Marburg virus and Ebola virus infections is serological tests and viral search, respectively.
• Treatment for Marburg virus and Ebola virus infections is convalescent serum and monoclonal antibodies.
• Vaccines for Marburg virus and Ebola virus are experimental.