glycolysis

• Catabolism of Glucose
• Glycogenolysis involves phosphorylase and debranching enzyme
• Phospho-gluco-mutase (PGM) is involved in the catabolism of glucose
• Glycolysis has an introduction and overview with 2 phases
• Phase I of glycolysis involves hexokinase, phospho-gluco-isomerase (PGI), phospho-fructo-kinase (PFK-1), aldolase, and triose-phosphate isomerase (TPI)
• Phase II of glycolysis involves glyceraldehyde-3-phosphate dehydrogenase
• Glucose utilization involves anabolism and catabolism
• Four major fates of glucose are discussed
• Phosphoglucose isomerase (PGI) is involved in setting up the second phosphorylation in glycolysis
• Phosphofructokinase-1 is the second phosphorylation step in glycolysis and is the first committed step
• Fructose-1,6-bisphosphate aldolase is involved in aldol cleavage/condensation in glycolysis
• Triose-phosphate isomerase (TIM) creates glyceraldehyde-3-phosphate (GAP) and dihydroxyacetone phosphate (DHAP) in glycolysis
• Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is the first energy-yielding step in glycolysis
• Phosphoglycerate kinase (PGK) is involved in substrate-level phosphorylation to make ATP in glycolysis
• Phosphoglycerate mutase (PGM) is involved in the dehydration of C3 and the formation of a high-energy phosphate compound in glycolysis