bindweefsel (histo1)

• Connective tissue provides structure, form and organization to the body.
• Collagen provides tensile strength to the ECM.
• Different types of connective tissue include fibrous, elastic, adipose, and cartilaginous tissue.
• Collagen is a protein found in all types of connective tissues.
• Proteoglycans are large molecules with long chains of sugar attached to protein cores.
• Glycosaminoglycans (GAG) are unbranched polysaccharides made up of repeating disaccharide units.
• Fibroblasts are the main cells of the

  connective tissue
• The extracellular matrix consists of the ground substance and the protein fibers
• The ground substance contains three (common) macromolecules, namely glycosaminoglycans (GAGs),

  proteoglycans and multi-adhesive glycoproteins.
• The GAGs often consist of hyaluronic acid, which provides firmness.
• Fibroblasten synthetiseren collageen, elastine en GAG’s
• Collageen is zeer sterk, zorgt voor vorm en stevigheid
• ECM bestaat uit collagene, reticulaire en elastine vezels