CP: avoid taking with other potassium elevating drugs
FDI: hyperkalemia risk inc with foods high in potassium (bananas, avocados)
S: none
Simvastatin
B: Zocor
C: HMG - CoA reductase inhibitors (statins)
I: hyperlipidemia / high cholesterol, prevent cardiovascular disease
CI: pregnancy category x
NSE: muscle pain, elevated liver enzymes, inc risk of diabetes type 2, headache
CP: inc risk of adverse effects with macrolide antibacterial drugs and amiodarone, typically take in the evening as they have greater effect bc diet intake is at its lowest
FDI: grapefruit juice inhibits metabolism which can lead to muscle dmg
S: none
Levothyroxine
B: Synthroid, Levoxyl
C: thyroid hormone
I: hypothyroidism, hypothyroidism secondary to hypopituitarism
NSE: diarrhea, weight loss, palpitations, tremors
CP: antacids reduce GI absorption, so administration should be separated by 4 hours to avoid interaction
FDI: foods high in multivalent ions (Ca, Fe, Mg, Al, Zn) reduce efficacy
S: none
Amoxicillin
B: Amoxil, Trimox
C: antibacterial penicillin
I: tonsillitis, bronchitis, pneumonia, ear / eye / skin infection, h. pylori infection (with PPI and macrolide)