Bacterial infection

• Osteomyelitis affect....

  Bone and marrow
• The bacteria that cause pyogenic osteomyelitis is staphylococcus aures
• Ideal site for multiplication of osteomyelitis is Metaphysis
• Pyogenic osteomyelitis is more common in children and adolescnets
• Dead piece of bone is called sequestrum
• New reactive bone is called involucrum and is stimulated by cytokines
• In chronic phase, sinuses appear as cloacae
• Complications of osteomyelitis

  • Spread of infection
  • Pathogenic fracture
  • Amyloidosis
  • Malignancy
• Vertebral tuberculosis is called Pott Disease
• Lower thoracic and upper lumber vertebrae are the most common sites in Pott Disease
• Pott disease is characterised by

  1. Kyphosis
  2. Cold abscess
  3. Paraplegia
• Comment on primary stage syphilis ulcer

  Rounded, superficial, flat egded, clean floor and firm margins
• Comment on gumma ulcer

  Sharp edges, necrotic floor, has punched out appearance and is pre-cancerous