a complete blockage of a coronary artery, usually due to the rupture of an atherosclerotic plaque causing a thrombus, leads to a large area of heart muscle being deprived of oxygen (ischemia)
This blockage causes significant and rapid damage to the heart tissue (necrosis), resulting in the release of large amounts of cardiac biomarkers, such as troponin
STEMI pt2:
On an ECG, STEMI is characterized by ST segment elevation, indicating severe myocardial injury
This blockage often requires immediate reperfusion therapy, such as a primary percutaneous coronary intervention (PCI) in order to restore blood flow and limit cardiac necrosis