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DNA replication
is the
process
by which DNA makes a
copy
of itself during
cell division.
3
parts
of
nucleotides
sugar
,
phosphate
,
nitrogenous
base.
Nitrogenous bases adenine
(A)
Thymine
(T and
DNA
Only
)
cytosine
(
C
)
guanine
(
G
) and
uracil
(
U
and
RNA
only
)
Dna stores genetic information
using its sequence of A´s T´s C´s and G´s
This
genetic information
is the
instructions
to make an
organism´s proteins
Dna-
Deoxyribonucleic
acid
Structure
of
DNA
it´s a
double helix
and is
double-stranded.
It's made of
deoxyribose sugar.
Its
nitrogenous bases
are
ATCG
What is the base strucure of DNA?
Double Helix
and
Double stranded
DNA
is
located
in the
Nucleus
RNA helps DNA make
protiens
3 types of
RNA mRNA
,
rRNA
and tRNa
RNA-
Ribonucleicacid
The
structure
of
RNA
is
single-stranded
with
NO double-helix.
It's
made
of
ribose sugar.
Its
nitrogenous bases
are
AUCG.
RNA is located in the Nucleus and Cytoplasm
A pairs
with
T
,
A pairs
with
U
and
C pairs
with
G
Whenever
cells divide
(
mitosis
),
DNA
must be
copied
DNA replication
is the
process
of making a
copy
of
DNA.
The
DNA
made during
DNA replication
is an
exact copy
of the
original DNA.
Since
replication
uses
existing DNA
as a
template
, it is
semiconservative.
Semiconservative
means that each
DNA molecule consists
of an
original strand
and a
new strand.
DNA strands
are connected by hydrogen bonds (weak).
Copying
DNA
requires
many
enzymes
(proteins).
Helicase separates DNA
strands
DNA Polymerase
-
adds nucleotides
and
proofreads
Ligase links new strands of DNA
The enzyme
helicase
“unzips”
or
separates
the
two strands
of
DNA.
DNA
polymerase
adds the
nucleotides
of the
new strands
using the
old strand
as a
template.
Finally,
ligase
links
together the
pieces
of
new DNA.
This idea that
DNA
→
RNA
→
Proteins
is called the
Central Dogma.
A section of DNA that codes for a
protein
is called a
gene.
Protein synthesis is the process of making
proteins.
Transcription is the first step in
protein synthesis.
Translation
is the
second
step
in
protein
synthesis.
Transcription
is located in the
nuclues
DNA unwinds where the gene is.
RNA polymerase
uses
DNA
as a
template
to make an
mRNA copy
(
transcript
).
Now the
mRNA copy
can leave the
nucleus.
codons
a sequence of 3 nucleotides that code for an
amino acid
(the building blocks of proteins)
mRNA
: carries DNA message as
codons
rRNA: makes up
ribosomes
tRNA
: matches
anti-codon
to
mRNA codon
to bring the correct
amino acid
The location of Translation is the
Cytoplasm
and
Rough-ER
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