Phospholipid bilayer has a polar head and non-polar tails, is a fluid bilayer, relatively impermeable to polar molecules
Non-polar molecules (O2, CO2, lipids) diffuse through freely
Smaller polar molecules (H2O, ethanol) diffuse through much more slowly
Larger polar molecules (glucose) diffuse through hardly at all
Phospholipid bilayer is a semipermeable membrane
Channel protein allows certain proteins to pass through the phospholipid bilayer with no control of direction of movement
Carrier protein picks up molecule and releases on the other side