Blood travels one circuit; blood flows through the heart and is pumped around the body before returning to the heart. Found in fish
Double circulatory system
Blood flows through the heart twice in two circuits. Blood is pumped from the heart to the lungs before returning to the heart. It is then pumped around the body, after which it returns to the heart again. Found in mammals
Open circulatory system
Transport medium pumped by the heart is not contained within vessels, but moves freely. The transport fluid comes into direct contact with the cells. Found in invertebrates, e.g. insects
Closed circulatory system
Blood pumped by the heart is contained within blood vessels. The blood does not come into direct contact with the cells. Found in animals, e.g. Vertebrates
Blood
The transport medium in the mammalian circulatory system. It consists of plasma, red blood cells, white blood cells and platelets
Artery
Carries blood away from the heart to the tissues, under high pressure. The walls contain collagen, smooth muscle and elastic fibres
Arteriole
Connects the arteries and capillaries. The walls contain large amounts of smooth muscle, some elastic fibres and some collagen
Vein
Carries blood towards the heart under low pressure. They have a wide lumen, a smooth inner lining and valves. The walls contain large amounts of collagen, smooth muscle and little elastic fibre
Venule
Connects the capillaries and veins. The walls contain small amounts of collagen and smooth muscle
Capillaries
Microscopic blood vessels that form a large network through the tissues of the body and connect the arterioles to the venules. They are the site of exchange of substances between the blood and the tissues
Tissue fluid
The fluid that surrounds the cells of animals. It has the same composition of plasma but does not contain red blood cells or plasma proteins
Lymph
Modified tissue fluid that drains into the lymphatic system. It carries less oxygen and fewer nutrients than tissue fluid, but also contains fatty acids
Plasma
The main component of the blood that carries red blood cells. It is a yellow liquid that contains proteins, nutrients, mineral ions, hormones, dissolved gases and waste
Aorta
The artery that takes oxygenated blood away from the heart to the body
Inferior vena cava
The vein that returns deoxygenated blood to the heart from the lower body
Superior vena cava
The vein that returns deoxygenated blood to the heart from the head and upper body
Atrioventricular (AV) valves
The valves found between the atria and ventricles. They prevent the backflow of blood from the ventricles into the atria. There are two types: bicuspid and tricuspid
Bicuspid valves
The atrioventricular valves found between the left atrium and left ventricle
Tricuspid valves
The atrioventricular valves found between the right atrium and right ventricle
Pulmonary arteries
The arteries that carry deoxygenated blood away from the heart to the lungs
Pulmonary veins
The veins that carry oxygenated blood from the lungs to the heart
Semilunar valves
A pair of valves found between the ventricles and arteries. They prevent the backflow of blood from the arteries into the ventricles
Septum
The wall of muscle which separates the left side of the heart from the right side of the heart, preventing oxygenated and deoxygenated blood from mixing
Myogenic
Describes cardiac muscle tissue that initiates its own contraction, without outside stimulation from nervous impulses
Cardiac cycle
Sequence of events involved in one complete contraction and relaxation of the heart. There are three stages: atrial systole, ventricular systole and diastole
Atrioventricular node (AVN)
A group of cells located between the atria that slow down the wave of excitation and pass it between the ventricles, along the bundle of His
Sinoatrial node (SAN)
A group of cells in the wall of the right atrium that generate electrical activity, causing the atria to contract. The SAN is often referred to as the heart's pacemaker
Purkyne tissue
Specialised cardiac muscle fibres which make up the bundle of His and conduct the wave of excitation through the septum, from the AVN down to the apex of the ventricles
Bundle of His
A collection of Purkyne fibres which run from the AVN down to the apex of the ventricles
Atrial systole
The stage of the cardiac cycle in which the atria contract, pushing blood into the ventricles. The AV valves are pushed open fully and the atria are emptied of blood
Diastole
The stage of the cardiac cycle in which the heart muscle relaxes. The atria and ventricles fill with blood
Ventricular systole
The stage of the cardiac cycle in which the ventricles contract, pushing blood into the arteries. The semi-lunar valves are pushed open fully
Heart rate
The number of times the heart beats in one minute
Hydrostatic pressure
The pressure exerted on the sides of a vessel by a fluid
Cardiac output
The volume of blood pumped by the heart through the circulatory system in one minute. It is calculated using the equation: cardiac output = heart rate × stroke volume
Electrocardiogram (ECG)
A technique used to indirectly measure the spread of electrical activity through the heart by measuring tiny changes in the skin's electrical conductivity. This produces a trace which is used to detect abnormalities in heart rhythm
Stroke volume
The volume of blood pumped by the left ventricle of the heart in a single contraction
Atrial fibrillation
An arrhythmia that involves the rapid contraction of the atria, preventing complete ventricular filling
Ectopic heartbeat
Additional heartbeats outside of the normal heart rhythm