Allele frequency is a measure of how common a specific allele is in a population. Allele frequency can be calculated using the formula:
All allele frequencies in a population must add up to 1.0. Allele Frequency = Number of copies of a specific allele Total number of alleles in a population
Sometimes there are more than 2 alleles for a gene in a population, e.g. ABO blood groups. Therefore, the denominator would be the total number of all the different alleles. It’s possible to calculate genotype and phenotype frequencies as well.
Scientists measure gene and allele frequencies and use the data to predict how external factors such as selective pressures influence these frequencies.
Allele frequency – how often we see each allele (W allele and w allele)
Genotype frequency – how often we see each allele combination (WW, Ww and ww)
Phenotype frequency – how often we see each phenotype (purple and white colour)