Cardiac cycle = sequence of events of oneheartbeat
3 stages of cardiac cycle:
atrial systole
ventricular systole
diastole
Atrial systole:
atrium walls contract and the blood pressure in the atria relaxes
pushes the blood through the tricuspid and bicuspid valves down into the ventricles, which are relaxed
Ventricular systole:
ventricle walls contract and increase the blood pressure in the ventricles
this forces the blood up through the semi-lunar valve, out of the heart, into the pulmonary artery and the aorta
blood cannot flow back from the ventricles into the atria as the tricuspid and bicuspid valves are closed by the rise of pressure in the ventricles
Pulmonary artery carries deoxygenated blood to the lungs and aorta carries oxygenated blood to the rest of the body
Diastole:
ventricles and atria relax
volume of ventricles and atrium increases -> pressure in the ventricles and atrium falls
risks the blood in the pulmonary artery and aorta from falling back into the ventricles
tendency to flow backwards causes the semi-lunar valve to shut
Atriums also relaxes -> blood from vena cava and pulmonary vein enters the atria and the cycle begins again
Heartbeat = complete contraction and relaxation of the whole heart
Two sides of the heart work together
atria contract at the same time followed by the ventricles
when a chamber contract, it is emptied of blood, relaxes-> filled with blood
atria walls have little muscle as they only have to push the blood to the ventricles
left ventricles have thicker muscles than the right ventricle
this is because the left ventricle have to pump the blood around the entire body whereas the right ventricle has to pump the blood to the lungs
Flow of blood (left side):
leftatriumrelaxes -> receives oxygenated blood from the pulmonary vein
when full, pressure forces open the bicuspid valve
relaxation of the left ventricle draws blood from the left atria
left atrium contracts -> pushes the remaining blood into the left ventricle through the valve
leftatriumrelaxed and bicuspid valve shut, to prevent back flow to the atria -> left ventricle contracts
pressure (from strong muscular walls) pushes blood up out of the heart through the semi-lunar valve into the aorta
sino-atrial node (SAN) = cluster of specialised cardiac cells in the walls of the right atrium, which acts as a pacemaker
atrio-ventricular node (AVN) = only conducting area of tissue in the wall of the heart between atria and ventricle (septum)
Control of heartbeat:
Wave of electrical stimulation arises at the sino-atrial node and spreads over both atria so they contract together, causing atrial systole
Electrical stimulation only spreads to the ventricle from the atrio-ventricularnode, introducing a delay in transmission of the electrical impulse
Muscles of the ventricles don’t begin to contract until muscles at the atria have finished contracting
Atrio-ventricular node passes the excitation down the nerves of the bundleofHis and to the apex of the heart
Excitation is transmitted to Purkinjefibres in the ventriclewalls, which carry it upwards through the muscles of the ventricle wall
Impulses cause the cardiac muscle in each ventricle to contract simultaneously, from the apex upwards, pushing blood up to the aorta and pulmonary artery, emptying the ventricles
Electrocardiogram (ECG) = trace of the voltage changes produced by the heart, detected by the electrodes on the skin
Tissue fluid = fluid that surrounds cells in tissues and is a mixture of plasma and fluid
Blood under pressure from the aorta due to the left ventricle contracting
Blood has a higher hydrostatic pressure compared to osmotic pressure, causing water and solutes to move out of the capillary down a concentration gradient by osmosis to the tissue surroundings
Solute, like mineral ions, diffuse into the tissue while waste products, such as carbon dioxide and urea, leave the tissue
As blood moves through the capillary, pressure decreases, making osmoticpressuregreater than hydrostaticpressure, leading to water and waste products moving back into the capillaries through osmosis
10% of the fluid drains into the lymph capillaries of the lymphatic system, eventually returning to the venous system through the thoracic duct, which empties into the left subclavian vein above the heart
In tissue fluid formation, red blood cells and plasma proteins are too big to pass the endothelial cell so they remain in the blood, which increase solute concentration as the blood moves across the capillary -> reason why tissue fluid is yellow instead of red
Tissue fluid:
bathes all cells
supply oxygen, glucose, hormones/ions to cell
remove waste from cells
Helps maintain a constant environment around cell
Action potential/ wave of depolarisation = when the cardiac muscle receives an electricalimpulse-> leads to cardiac muscle contract (systole)