The nucleus is the control center of the cell, containing genetic material (DNA) that determines an organism's characteristics.
Nucleolus - A small dense body within the nucleus where ribosomes are produced.
Chromatin - The substance made up of DNA and proteins found inside the nucleus.
Ribosome - Small structures involved in protein synthesis.
Cell membrane - Also known as plasma membrane or plasmalemma, it separates the contents of the cell from its surroundings and regulates what enters and exits the cell.
Cytoplasm - The fluid-like substance inside the cell that contains various structures such as mitochondria, endoplasmic reticulum, Golgi apparatus, lysosomes, cytoskeleton, and ribosomes.
Mitochondria - Organelles responsible for producing energy through respiration.
Endoplasmic reticulum (ER): A network of membranes involved in protein production and lipid transport.
Cytoplasm - The jelly-like fluid surrounding the nucleus and other organelles.
Endoplasmic reticulum - Network of membranes involved in protein production and transport.
Golgi Apparatus: Modifies and packages proteins produced by the ER for export outside the cell.
Lysosomes: Membranous sacs containing digestive enzymes used to break down waste materials within cells.
Cytoskeleton: Network of fibers that provides structural support and helps maintain cell shape.
Cell Wall: Provides structural support and protection against pathogens.
Vacuoles: Large, membrane-bound structures that store water, nutrients, or waste products.
Microtubules: Long, hollow tubes made up of globular subunits called tubulin.
Plasma Membrane: Regulates the movement of substances into and out of the cell.
Centrioles: Pair of cylindrical structures composed of microtubules found near the nucleus.
Chloroplasts: Organelles found only in plant cells that contain pigments called chlorophyll and are responsible for photosynthesis.
Centrosome: Contains microtubule organizing centers (MTOC) responsible for organizing microtubules during mitosis.
Flagella/Cilia: Whip-like appendages on some eukaryotic cells involved in movement.
Chromatin: DNA wrapped around proteins to form chromosomes.
Cell Theory:
Discovered in 1665 by Robert Hooke
Early studies conducted by Mathias Schleiden (1838) and Theodor Schwann (1839)
Proposed the Cell Theory:
1. All organisms are composed of cells
2. Cells are the smallest living things
3. Cells arise only from pre-existing cells
All cells today represent a continuous line of descent from the first living cells
Cell size limitations:
Most cells are relatively small due to reliance on diffusion of substances
Rate of diffusion affected by surface area available, temperature, concentration gradient, and distance
Cell surface area must be large enough to meet the metabolic needs of its volume
Cell surface area and volume:
As a cell gets larger, its volume increases at a faster rate than its surface area
Cell's surface area must be large enough to meet the metabolic needs of its volume
Organisms made of many small cells have an advantage over those composed of fewer, larger cells
Microscopes and cell visualization:
Not many cells are visible to the naked eye
Resolution is the minimum distance two points can be apart and still be distinguished as two separate points
Two types of microscopes: Light microscopes and Electron microscopes
Prokaryotic Cell:
Basic structural similarities include nucleoid or nucleus, cytoplasm, ribosomes, and plasma membrane
Simplest organisms lacking a membrane-bound nucleus
Cell wall outside of plasma membrane
Two domains of prokaryotes: Archaea and Bacteria
Prokaryotic cell structure:
Generalized cell organization of a prokaryote
Nucleoid visible as a dense central region segregated from the cytoplasm
Some prokaryotes have hairlike growths called pili on the outside of the cell
Bacterial cell walls:
Most bacterial cells are encased by a strong cell wall composed of peptidoglycan
Protect the cell, maintain its shape, and prevent excessive uptake or loss of water
Susceptibility of bacteria to antibiotics often depends on the structure of their cell walls
Prokaryotic flagella:
Present in some prokaryotic cells for locomotion
Rotary motion propels the cell forward
Eukaryotic Cell:
Possess a membrane-bound nucleus
More complex than prokaryotic cells with compartmentalization achieved through membrane-bound organelles
Possess a cytoskeleton for support and to maintain cellular structure
Animal vs. plant cells:
Both have plasma membrane and most organelles
Plant cells have extra components like a cell wall, chloroplasts, and specialized vacuoles
Nucleus:
Repository of genetic information
Most eukaryotic cells possess a single nucleus with a nucleolus for ribosomal RNA synthesis
DNA organized into multiple linear chromosomes with proteins into chromatin
Ribosomes are the cell's protein synthesis machinery found in all cell types in Archaea, Bacteria, and Eukarya
Ribosomes consist of a large and a small subunit composed of rRNA and protein
The individual subunits of ribosomes are synthesized in the nucleolus and then move through the nuclear pores to the cytoplasm, where they assemble to translate mRNA
Ribosomes serve as sites of protein synthesis
Endomembrane system is a series of membranes throughout the cytoplasm that divides the cell into compartments where different cellular functions occur
One of the fundamental distinctions between eukaryotes and prokaryotes is the presence of the endomembrane system in eukaryotes
Endoplasmic reticulum (ER) consists of rough ER (RER) and smooth ER (SER)