An example of the interactionist approach is the diathesis-stress model, which suggests that mental illness originates through the combination of an underlying vulnerability (diathesis) and a stress trigger
Meehl originally applied the diathesis-stress model to schizophrenia, suggesting vulnerability to schizophrenia was entirely genetic due to a single "schizogene"
Recent understanding has evolved to show that vulnerability can result from psychological trauma in childhood, not solely genetics, and stress triggering schizophrenia can be non-psychological
In the real world, the diathesis-stress model has shown effectiveness in combining biological and psychological treatments for schizophrenia, leading to superior treatment outcomes
Research by Tienari et al. supports the interactionist approach by showing that parenting styles with high criticism and conflict are associated with developing schizophrenia in children of schizophrenic mothers
The original diathesis-stress model is considered too simplistic as stress factors can include biological influences, such as childhood sexual abuse and increased cannabis use, which can affect vulnerability and stress levels