It is associated, however, with multiple distention, dehydration, stress, and infection/ inflammation. Women who continue to work at strenuous jobs during pregnancy or perform shift work that leads to extreme fatigue and stress may trigger the labor. Chronic stress causes long-term changes in the body's vascular system, hormone levels, and the ability to fight infection. With the increased stress, the cortisol hormone appears to cross the placenta and affect the fetus, disrupting ongoing processes. These changes could all potentially influence labor to start before the baby is full-term. These chemicals pass through the placenta into the fetus and have detrimental effects on proper fetal growth. The overproduction of prostaglandins caused by the inflammation associated with an infection could lead to uterine contractions.