A reoccurrence of the BlackDeath hit London in 1665 killing around 100,000 - 20% of the population. The rich fled but doctors and priests were most affected as they dealt with the sick.
Believed the Great Fire of London sterilised parts of London by burning down cramped houses killing bacteria.
The Great Plague had a devastating impact as the cause was unknown and there were no national government responses.
During the Great Plague, local Councils quarantined victims and painted a red cross on their door, banned crowded areas e.g. theatres, people had limited contact, mass graves and the execution of cats and dogs.
Preventions for the Great Plague were ineffective due to lack of understanding . Poor living conditions, poverty and overcrowding accelerated the Plague.