1. Occurs in phagocytes such as neutrophils, macrophages, and dendritic cells
2. Involves targeting pathogens coated in opsonins
3. Steps include attachment, engulfment, phagosome formation, recruitment of lysosomes, fusion, and microbe killing
4. Requires membrane rearrangement and opsonins
5. Microbe killing due to reactive oxygen species, defensins, hydrolytic enzymes, and low pH in phagolysosome
6. Neutrophils release azurophilic and specific granules, as well as neutrophil extracellular traps