Respiring cells use oxygen in respiration and produce carbon dioxide; therefore respiring cells will have low p02 and a high pCO2. When pCO2 is high the rate of oxygen dissociation increases.
The increased dissociation of oxygen will cause a shift in the oxyhaemoglobin curve to the right. This shift means that the oxygen will dissociate form haemoglobin at a lower rate than normal. This is called the Bohr effect.