Reverse transcriptase is found in viruses with RNA genomes and synthesizes a double-stranded DNA copy of a viral RNA gemome
Integrase integrates the viral DNA into the host DNA which will now produce viral proteins from the viral DNA
the lytic cycle is characterized by massive reproduction of the virus resulting in host cell lysis therefore it is virulent
in the lysogenic cycle, the virus enters into a latent state where it does not reproduce but remains dormant within the host cell until triggered to become active again
in the lytic cycle viral DNA replicated separately from the bacterial chromosome
in the lysogenic cycle viral DNA is integrated into the bacterial chromosome
RNA-dependent-RNA polymerase synthesizes negative sense ssRNA in sars-cov-2
the information flow of gene expression in the sars-cov-2 life cycle is RNA +, RNA -, RNA +, protein