practice q's 2

• An individual who is lactase persistence will also have hydrogen in their breath when doing a Breath Hydrogen Test. True or flase?

  false
• Following the activation of a gluten specific naive CD4+ T cell (Th0), which transcription factor will direct its differentiation into T helper 1 cell?

  Tbet
• What component is a key in cell apoptosis?

  Perforin, it is released from granules and pokes holes in the cell membrane, triggering apoptosis
• What other symptom is directly associated with lactose intolerance?

  bloating
• how does activated IELs (intraepithelial lymphocytes) engage in a cell contact-dependent mechanism to mediate apoptosis?

  Binding FasLigand on IELs to Fas on the surface of the target cell
• What combination of dietary bioactives and mechanisms will lead to decreased bone resorption?

  Long chain n-3 PUFA and decreased RANK-L secretion
• What mechanism is responsible for absorption of monosaccharides such as glucose and galactose into enterocytes?


  Co-transport with sodium ions via SGLT1
• What destroys the connective tissue sheath around muscle layers of the small intestine?

  anti-endomysium antibodies
• what proteins are under calcitriol control?

  TRVP6, calbindin, sodium calcium exchanger, calcium pump on basolateral membrane