Effects of mutations on the function of enzymes

• what are the consequences of a mutation in the bases of the DNA on the activity on enzymes?

  • changes based (primary structure)
  • bases of DNA code for order of bases in mRNA
  • changing a codon, changes the order of amino acids in the primary structure of the protein
  • this in turn can affect the tertiary structure of the protein, which in turn can lead to faulty or non-functioning enzymes