In the body enzymes optimum temperature is 37 degrees celcius.
As we increase the temperature of an enzyme, the activity increases due to more collisions per second between the substrate and the active site.
If we increase the temperature of an enzyme past optimum, its activity starts to fall. This is because the vibrations change the shape of the active site, eventually denaturing it so it no longer works.
Each enzyme has a specific pH that they work best at.
