Life-threatening complications of orofacial infections
Ludwig’s angina
Mediastinitis
Involvement of carotid sheath
Intracranial complications like cavernous sinus thrombosis, brain abscess, dural meningitis, and osteomyelitis of the skull
Retrobulbar cellulitis leading to blindness
Ludwig’s angina is related to the lower jaw
Ludwig’s angina is a firm, acute, toxic, and severe diffuse cellulitis/induration that spreads rapidly, bilaterally affecting the submandibular, sublingual, and submental spaces
Wilhelm Friedreich Von Ludwig coined the term ‘Ludwig’s angina’ in 1836
Classic Ludwig angina
Definite bilateral involvement of all three spaces: submandibular, sublingual, and submental spaces
In classic Ludwig angina, it was to be feared, rarely became fluctuant, and was often fatal
Other names for Ludwig’s angina
Marbus strangulatorius: chocking effect of the disease
Angina maligna
Garrotillo: Spanish version for Hangman’s knot (noose)
Odontogenic infections account for 90% of Ludwig’s angina cases, mainly affecting the second and third mandibular molars
Aetiology of Ludwig’s angina
Odontogenic infection
Traumatic injuries of orofacial region
Submandibular and sublingual sialadenitis
Secondary infections of oral malignancies
Pharyngeal infection or tonsillitis
Iatrogenic: Use of contaminated needle for giving local anaesthesia
Cervical lymphoid tissues
Miscellaneous: Foreign bodies such as fish bone
Pseudo-Ludwig’s angina/pseudo-Ludwig’s phenomena are cases of non-dental origin
Microbiology of Ludwig’s angina
Streptococci
Mixed oral flora including staphylococci, E. coli, Pseudomonas, and anaerobes like Bacteroides, Peptostreptococcus, Prevotella species, fusospirochetes
Clinical features of Ludwig’s angina
General constitutional symptoms: looks toxic, very ill, dehydrated
Chills and malaise
Marked pyrexia
Difficulty in swallowing (dysphagia)
Impaired speech and hoarseness of voice
Extraoral examination findings in Ludwig’s angina
Bilateral suprahyoid swelling
Swelling is firm/hard, brawny, nonpitting
Bacteria
fusospirochetes
Isolation conditions
Anaerobes
Clinical features
General constitutional symptoms: looks toxic, very ill, dehydrated
Chills and malaise
Marked pyrexia
Difficulty in swallowing (dysphagia)
Impaired speech and hoarseness of voice
Extraoral examination
1. Bilateral suprahyoid swelling
2. Swelling is firm/hard, brawny, nonpitting, not-fluctuating and tender on palpation
3. Airway obstruction and cyanosis may occur
4. Difficulty in swallowing and breathing
5. Early presentation has no suppuration but...
Extraoral examination
Mouth remains open
Shallow breathing
Restricted mouth opening
Fatal death, 10–24 h due to asphyxia
Intraoral examination
1. Swelling develops rapidly
2. Increased salivation, stiffness of tongue, difficulty in swallowing with hot potato speech is noted
3. Drooling of saliva
4. Backward spread of infection leading to oedema of the glottis
5. Development of Stridor
Potential complications
Septicaemia, upper respiratory airway obstruction and provoke oedema of the epiglottis
Mediastinum, producing thoracic empyema
Aspiration pneumonia and vascular erosion
Common cause of mortality is acute obstruction of the airways
Reach close to carotid sheath
Pterygopalatine fossa, leading to cavernous sinus thrombosis
Fatal within 12–24 h due to asphyxia
Diagnosis
Clinical findings, although CT studies
Treatment
1. Early with administration of antibiotics
2. Prophylactic incision
3. Airway must also be controlled
Surgical management
1. In case of rise of tissue tension, little amount of pus is evacuated
2. Bilateral drainage of submandibular spaces with the drainage of sublingual and submental spaces
3. Drain sublingual and submental spaces separately to avoid perforation of the mylohyoid muscle
Distant spread
1. Spread can occur by means of the bloodstream
2. Via internal jugular vein
3. Cardiac colonization
4. Cavernous sinus
5. Encephalic abscesses and meningitis
Fascia
A band or sheet of connective tissue, primarily collagen, beneath the skin that attaches, stabilizes, encloses, and separates muscles and other internal organs
Shapiro defined fascial spaces as potential spaces between the layers of fascia. These spaces are normally filled with loose connective tissues and various anatomical structures like veins, arteries, glands, lymph nodes, etc.
Maxillary primary spaces
Canine space
Involvement in Canine space
Odontogenic infections
Nasal infections; less frequent
Teeth frequently giving rise to abscess in the area
Maxillary canines
Premolars
Mesiobuccal root of first molars
Contents of Canine space
Angular artery and vein
Infraorbital nerve
Clinical features of Periapical abscess of canine
1. Present as labial sulcus swelling and less commonly as palatal swelling
2. Swelling of the cheek and upper lip (vestibular abscess)
3. Obliteration of the nasolabial fold (pus accumulation in the nasolabial fold)
4. Oedema of the lower eyelid
5. Marked periorbital oedema forcing the eyelid to close
6. Marked tenderness and redness in the facial tissue
Surgical management of Periapical abscess of canine
The incision is made intraorally high in the maxillary labial vestibule. Insert a small haemostat through the levator anguli oris into the abscess cavity, place a rubber drain and suture into the lower margin of the vestibular incision
Involvement in Palatal abscess
Periodontal abscesses from palatal pockets and apical abscesses from the palatal roots
Surgical anatomy of Palatal abscess
Boundaries: cortical plate of hard palate inferiorly, and the overlying periosteum and mucosa superiorly; and laterally by the alveolar process of maxilla and the teeth
Involvement in Buccal Space
Buccinator and masseter muscle
Boundaries of Buccal Space
Superior: Zygomatic arch
Inferior: Inferior border of mandible
Anterior: Posterior border of the zygomatic bone above and depressor angulioris below
Posterior: Anterior border of the masseter muscle
Medial: Buccinator muscle and its fascia
Lateral: Skin and subcutaneous tissue
Buccal space
The potential space between buccinator and masseter muscle
Boundaries of the buccal space
Superior - Zygomatic arch
Inferior - Inferior border of mandible
Anterior - Posterior border of the zygomatic bone above and depressor angulioris below
Posterior - Anterior border of the masseter muscle
Medial - Buccinator muscle and its fascia
Lateral - Skin and subcutaneous tissue
Contents of the buccal space
Space filled with buccal pad of fat (adipose tissues)
Parotid duct
Anterior and transverse facial artery and vein
Surgical management of spread
1. Continuation with pterygomandibular space
2. To infratemporal space along the fascia accompanying the Stenson's duct
3. To submasseteric space if infection tracks backwards and penetrates the paratidomassetric fascia
Infratemporal space
Also called as 'retro-zygomatic space' as it is partly situated behind the zygomatic bone