pedigree charts

• Autosomal dominant inheritance - If both parents are affected and an offspring is unaffected, the trait must be dominant(Both parents are heterozygous)
• Autosomal dominant - In the case of a disease, homozygous effects are rare as they will always have affected offspring, meaning that lineage is often short-lived
• Autosomal recessive - If both parents are unaffected and an offspring is affected, the trait must be recessive
• Dominant - Allele mask recessive allele
• Recessive - 2 recessive alleles so that recessive trait can be expressed
• X-linked dominant disorders are caused by a mutation on the X chromosome
• X-linked recessive disorders are caused by mutations in genes on the X chromosome