Biological

Cards (2)

  • Genetics
    • OCD runs in families, Inherit a genetic predisposition (risk) to OCD
    • Closer genetic link higher likelihood (concordance)
    • Identical twin concordance is (87%) compared to non-identical 47% concordance
    • Two genes have been linked to OCD
    • SERT – Less serotonin as it is soaked up before it reaches the next neuron (increases anxiety)
  • Neural
    • OCD is due to imbalance of neurotransmitters
    • Serotonin is linked to maintaining a stable mood
    • Serotonin levels are low in those with OCD which can lead to anxiety
    • Low serotonin could be due to serotonin being removed too quickly in the synapse before it can activate the next neuron.
    • Basal Ganglia – responsible for psychomotor skills, this is hypersensitive in those with OCD so it leads to repeated (compulsive) behaviours